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A U1-U3 snRNA-snoRNA interaction couples SF3B1 mutation to chromatin-state rewiring and genome instability

Xia, P., Li, H., Ji, Y., Ju, C.-w., Pan, Y., Mo, J., Zhu, X., Zhao, L., Lyu, R., Niewold, E., et al.
10.64898/2026.06.06.722969 · was preprinted
discovery code ↗ data available
Surfaced because: unusual independent discussion, open code, data available.
relevance 0.43 openness 0.50 novelty 0.35 attention 0.81

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Moderated digest of third-party discussion on Bluesky — substantive endorsement and critique.

  • Aaron and the Hoskins Lab at UW Madison @uwmadisonrna.bsky.social · 595 followers neutral

    Huh... some head scratching here... www.biorxiv.org/content/10.6... A U1-U3 snRNA-snoRNA interaction couples SF3B1 mutation to chromatin-state rewiring and genome instability Peng Xia, , Omar Abdel-Wahab, Bei Liu, Chuan He et al...

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  • bioRxivpreprint @biorxivpreprint.bsky.social · 8893 followers neutral

    A U1-U3 snRNA-snoRNA interaction couples SF3B1 mutation to chromatin-state rewiring and genome instability https://www.biorxiv.org/content/10.64898/2026.06.06.722969v1

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  • bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 6027 followers neutral

    A U1-U3 snRNA-snoRNA interaction couples SF3B1 mutation to chromatin-state rewiring and genome instability https://www.biorxiv.org/content/10.64898/2026.06.06.722969v1

    ♡ 0 ⇄ 0 💬 0 view on Bluesky ↗