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Benchmarking gene expression reconstruction from single-cell latent representations

Fu, X., Klein, D., Antipov, E., Palma, A., Tejada-Lapuerta, A., Bahrami, M., Kummerle, L. B., Lubetzki, M., Casale, F. P., Luecken, M. D., et al.
10.64898/2026.06.15.731445 · was preprinted
method development code ↗ data available preregistered benchmarked
Surfaced because: open code, data available, preregistered, benchmarked against baselines.
relevance 0.45 openness 1.00 novelty 0.35 attention 0.49

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  • AI x Bio Discovery @aixbiobot.bsky.social · 791 followers neutral

    Benchmarking gene expression reconstruction from single-cell latent representations [new] evaluates how well latent representations enable gene-level analysis, vital for biological interpretability and virtual cell models.

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