Rising — Salient

Bacterial Hsp70 DnaK transiently samples the proteome to rapidly capture stress-induced misfolding

1d · Pajari, A., Redchuk, T., Mäkelä, J. · biorxiv

discovery top 2% discussedtop 6% novel

Surfaced because: unusual independent discussion.

💬 4 discussion

Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition

1d · Gonzaga-Saavedra, N., Degen, E. A., Soluri, I. V., et al. · biorxiv

discovery top 2% discussed

Surfaced because: unusual independent discussion.

💬 5 discussion

Cellular Stress Tolerance Governs Genetic Transformability in Recalcitrant Candida Species

1d · Cotter, C. J., Carper, D. L., Giannone, R. J., et al. · biorxiv

discovery top 1% novel

Surfaced because: novel vs its neighbours.

Targeted DNA nicking enables efficient, single-step and counterselection-free editing of bacteriophage genomes

1d · Englert, F., Valappil, S. K., Kubilius, J., et al. · biorxiv

discovery top 8% novel

Surfaced because: matches the platform's topic region.

💬 2 discussion

Synergistic CRISPR-Cas Antimicrobials through Essential and Defensive Gene Cotargeting in Staphylococcus aureus

1d · Dooley, D. S., Trinh, C. T. · biorxiv

discovery benchmarked top 7% novel

Surfaced because: benchmarked against baselines.

💬 2 discussion

Mechanochemical Feedback Enables Efficient Navigation in Complex Chemical Gradients

1d · Huras, E., Algorta, J., De Belly, H., et al. · biorxiv

discovery top 5% novel

Surfaced because: matches the platform's topic region.

Robust axis formation requires both short-range adhesion and long-range attraction

1d · Guan, G., Wang, S., Shields, T. G., et al. · biorxiv

discovery top 6% novel

Surfaced because: matches the platform's topic region.

USP7 maintains hematopoietic stem cell dormancy and function by stabilizing HMGA2

1d · Nouhaud, A., Diaz, A., Bouttier, M., et al. · biorxiv

discovery top 6% novel

Surfaced because: matches the platform's topic region.

💬 1 discussion

Regulation of RNA maturation by the family of human G-patch proteins

1d · Memet, I., Kanwal, N., Ritchie, A., et al. · biorxiv

discovery top 3% novel

Surfaced because: matches the platform's topic region.

Telomerase RNA regulates the epigenome primed for human lineage commitment

1d · Li, J., Su, P., Gao, M., et al. · biorxiv

discovery top 3% novel

Surfaced because: matches the platform's topic region.

HSPB8 regulates CTP synthase filaments to couple nucleotide metabolism and autophagy in tumors

1d · Wang, C.-Y., Lin, W.-C., Huang, K.-J., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

💬 2 discussion

LINE-1 transposon derived DNA lesions reshape the chromatin landscape to promote genome instability

1d · Kumar, A., Parida, A. S., Kiran, K., et al. · biorxiv

discovery top 10% novel

Surfaced because: matches the platform's topic region.

A cinnamyl alcohol dehydrogenase-like scaffold organizes monoterpenoid indole alkaloid biosynthesis

1d · Gao, D., Alexander Mann, S. G., Chen, B., et al. · biorxiv

discovery top 8% novel

Surfaced because: matches the platform's topic region.

Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

1d · Wang, P.-K., Lin, K.-h., Tang, T. K. · biorxiv

discovery

Surfaced because: unusual independent discussion.

💬 3 discussion

The human leukemic fusion protein MLL-AF4 promotes autophagy and cell death in the fat body of Drosophila melanogaster

1d · Haukeland, A. L. C., Johannessen, J. A., Brathen, N. R., et al. · biorxiv

discovery top 6% novel

Surfaced because: matches the platform's topic region.

💬 2 discussion

Fast assembly and in vivo coalescence of ParBF biocondensates involved in bacterial DNA partition

1d · Revoil, P., Delimi, L., Rech, J., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

Solid-like PAR protein assemblies encode long-term spatial memory of cell polarity during suspended animation

1d · Borrego-Pinto, J., Cornwall Scoones, J., Hirani, N., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

💬 2 discussion

Impact of coding region accessibility and uridine chemistry on translation in mRNA-DNA hybrid origami

1d · DAmico, C., Mykkänen, M., Saarinen, S., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

💬 2 discussion

Aberrant 3'UTR splicing drives FUS-dependent mRNA condensates and prevents β-catenin from adherens junctions to promote cancer aggressiveness

1d · Hong, D., Kim, N., Jo, Y., et al. · biorxiv

discovery top 8% novel

Surfaced because: matches the platform's topic region.

💬 2 discussion

RNA dysregulation and compromised neuronal identity drive pathogenesis in Senataxin-associated ALS

1d · Giannini, M., Gostan, T., El Aabidine, A. Z., et al. · biorxiv

discovery top 7% discussed

Surfaced because: unusual independent discussion.

💬 2 discussion

Single-molecule imaging reveals cytoplasmic translation of P granule-enriched mRNAs in C. elegans

1d · Simmons, W. R., Geng, Q., Miller, S. I., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

💬 2 discussion

Sequence determinants of efficient exon 44 skipping in Duchenne muscular dystrophy define design principles for steric-blocking antisense oligonucleotides

1d · Han, E., Webster, K., Stan, T. L., et al. · biorxiv

discovery benchmarked

Surfaced because: benchmarked against baselines.

Masking phosphatidylserine prevents neuronal loss in two distinct Drosophila models of neurodegeneration

1d · Khateb, N., Shwartsburd, M., Grig, E., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

💬 3 discussion

Organization and triggered release of liposomes with DNA-based synthetic condensates

1d · Tanase, D. A., Malouf, L., Rubio-Sanchez, R., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

Antimicrobial-resistance plasmids encode Evangelion, a widespread DUF4062 anti-phage defence family

1d · Ibarra-Chavez, R., Azam, A. H., Chihara, K., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

💬 1 discussion

Transcription terminators with context-dependent promoter and terminator activities

1d · Bao, L., Forster, A. C. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

WRNIP1-ATM signaling promotes G-quadruplex resolution by preserving FANCJ stability

1d · Valenzisi, P., Parrillo, R., Pichierri, P., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

Sequential adaptor function of Treacle and MDC1 couples nucleolar reorganization to RNF8-dependent recruitment of HDR factors

1d · Haenel, A., Leyrer, J., Stutz, P., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

Mitochondria-ER contacts restrain store-operated Ca{superscript 2}⁺ entry via Ca{superscript 2}⁺ flickering and STIM1 trapping

1d · Lin, Y.-C., Sung, C.-J., Lin, Y.-C., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.

Cooperative motility emerges in crowds of T cells and prevents jamming

1d · Wortel, I. M., Postat, J., Mihaylova, M., et al. · biorxiv

discovery

Surfaced because: matches the platform's topic region.